Poster presentations - Drug abuse and dependence

Kuijer E, Heal D, Bailey S, Smith S, Wonnacott S, Bailey C. Kappa opioid receptor currents in mouse paraventricular thalamus. International Narcotics Research Conference, Valencia, Spain, July 2022.

Synan C, Bowen C, Heal D, Froger-Colleaux C, Beardsley P, Campbell U. SEP-363856, a Novel TAAR1 Agonist, Lacks Abuse Liability in Preclinical Models and Attenuates Cocaine Cue-Induced Relapse in Rats. American College of Neuropsychopharmacology (ACNP) 59th Annual Meeting, December 2020.

Heal D, Rowley H, Smith S, Elbekai R. Evaluation of the Discriminative and Reinforcing Potential of Centanafadine and Reference Comparator ADHD Drugs by Drug-Discrimination and Intravenous Self-Administration Testing in Rats. American College of Neuropsychopharmacology (ACNP) 59th Annual Meeting, December 2020.

Coccia MJ, Wonnacott S, Heal DJ, Bailey CP.  The role of alpha7 nicotinic receptors in the ventral hippocampus in heroin-induced conditioned place preference. Federation of the European Neuroscience Societies, July 2020.

Synan C, Bowen C, Heal DJ, Froger-Colleaux C, Beardsley PM, Campbell U, Koblan KS. Preclinical abuse liability assessment of the novel psychotropic, SEP-363856. College on Problems of Drug Dependence Meeting, June 2020.

Heal DJ, Smith SL. Relative contributions of drug re-exposure and salient cues in the reinstatement of cocaine and heroin seeking; implications for the treatment of substance use disorders. American College of Neuropsychopharmacology Meeting, Dec 2019.

Gray RA, Heal DJ, Maguire DR, Gerak LR, Javors MA, Smith SL, France CP. Investigation of the reinforcing and discriminative properties of highly purified botanical cannabidiol in rats and monkeys. American College of Neuropsychopharmacology Meeting, Dec 2019.

Smith SL, Heal DJ. How reinforcing is bupropion? Comparison with methylphenidate and cocaine by intravenous self-administration in rats. Society for Neurosciences Congress, Oct 2019.

Coccia MG, Wonnacott S, Heal DJ, Bailey CP. The role of α7 nicotinc receptors in reinstatement of drug-induced conditioned place preference. European Behavioural Pharmacology Society, Aug 2019.

Rowley HL, Kulkarni RS, Heal DJ. Dopamine measurement by in vivo microdialysis as a rapid, early screen to detect the abuse potential of novel CNS-active drug-candidates. Safety Pharmacology Society Meeting, Sept 2019.

Jagger L, Heal DJ, Cheetham SC. Ex vivo receptor binding in rats as a rapid screen for CNS penetration and occupancy of abuse-related molecular targets. Safety Pharmacology Society Meeting, Sept 2019.

Heal DJ, Gosden J, Smith SL. An evidence-based evaluation of the possible influence of gender on results from abuse and dependence liability testing in rats. College on Problems of Drug Dependence Meeting, June 2019.

Smith S, Hallam M, Turnbull Z, Roberson D, Painter M, Yekkirala A, Heal D. An investigation of the reinforcing potential of Blue-181 in rats trained to self-administer heroin. College on Problems of Drug Dependence Meeting, June 2019.

Palandri J, Bailey C, Heal DJ, Kendall D. An investigation of the reinforcing potential of PN6047 by conditioned place preference testing in rats. College on Problems of Drug Dependence Meeting, June 2019.

Heal DJ, Holland S, Gosden J, Gray RA, Smith SL. An investigation of the discriminative stimulus and reinforcing effects of cannabidiol in rats. Society for Neurosciences Congress, Oct 2018

Smith SL, Hallam M, Heal DJ. Determination of the relative reinforcing effect of MDMA by fixed ratio (FR) and progressive ratio (PR) intravenous self-administration testing in rats. Society for Neurosciences Congress, Oct 2018.

Smith SL, Holland SJ, Slade J, Hallam M, Heal DJ. Progressive ratio (PR) intravenous self-administration testing in rats to assess the relative reinforcing effects of a wide range of substances of abuse. Safety Pharmacology Society Meeting, Sept 2018.

Smith S, Keogh E, Holland H, Slade J, Heal D. Investigation of the reinforcing effect of barbiturates and benzodiazepines in rats trained to self-administer heroin. British Association of Psychopharmacology Meeting, July 2018.

Keogh E, Smith SL, Heal DJ. Comparison of the reinstatement of cocaine-seeking in remission induced by cues, drug or a drug/cue combination – an IVSA study in rats. College on Problems of Drug Dependence Meeting, June 2018.

Goddard S, Heal DJ, Smith SL. A comparison of the physical dependence syndromes produced in rats by morphine and diazepam. College on Problems of Drug Dependence Meeting, June 2017.

Smith SL, Holland S, Gray RA, Heal DJ. An investigation of the reinforcing effects of diazepam and midazolam in rats trained to self-administer heroin. College on Problems of Drug Dependence Meeting, June 2017.

Heal DJ, Smith SL. Comparison by rat intravenous self-administration (IVSA) of the reinforcing effects of nicotine versus three C-II drugs. College on Problems of Drug Dependence Meeting, June 2017.

Heal DJ, Goddard S, Gosden J, Dykes S, Slater N, Brammer R, Spencer R, Menzaghi F. A preclinical evaluation of the potential of CR845 to induce tolerance and a syndrome of dependence on withdrawal. American College of Neuropsychopharmacology Meeting, Dec 2015.

Heal DJ, Gosden J, Slater N, Holland SJ, Slade J, R. Spencer R, Menzaghi F, Smith SL. Investigation of the discriminative and reinforcing properties of the κ opioid receptor agonist CR845 in rats. Society for Neurosciences Congress, Oct 2016.